MiR-27a promotes insulin resistance and mediates glucose metabolism by targeting PPAR-γ-mediated PI3K/AKT signaling

This study aimed to establish a high-fat diet (HFD)-fed obese mouse model and a cell culture model of insulin resistance (IR) in mature 3T3-L1 adipocytes. A dual-luciferase reporter assay (DLRA) was confirmed interaction between miR-27a and the 3′-untranslated region (UTR) of Peroxisome proliferator...

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Detalles Bibliográficos
Autores principales: Chen, Tianbao, Zhang, Yi, Liu, Yilan, Zhu, Dexiao, Yu, Jing, Li, Guoqian, Sun, Zhichun, Wang, Wanru, Jiang, Hongwei, Hong, Zhenzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781997/
https://www.ncbi.nlm.nih.gov/pubmed/31562809
http://dx.doi.org/10.18632/aging.102263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781997/
https://www.ncbi.nlm.nih.gov/pubmed/31562809
http://dx.doi.org/10.18632/aging.102263

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