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Upregulation of miR-93 and inhibition of LIMK1 improve ventricular remodeling and alleviate cardiac dysfunction in rats with chronic heart failure by inhibiting RhoA/ROCK signaling pathway activation

Objective: There are some researches about the role of microRNA (miRNA) in chronic heart failure (CHF) were performed, but the study about miR-93’s function in CHF is scarcely investigated. Thus, we determined to probe into the effects of miR-93 in rats with CHF by targeting LIMK1 through regulating...

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Detalles Bibliográficos
Autores principales: Su, Qian, Zhang, Peng, Yu, Dong, Wu, Zhaodi, Li, Dandan, Shen, Fangfang, Liao, Pengfei, Yin, Guizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782012/
https://www.ncbi.nlm.nih.gov/pubmed/31541994
http://dx.doi.org/10.18632/aging.102272