PTPRU, As A Tumor Suppressor, Inhibits Cancer Stemness By Attenuating Hippo/YAP Signaling Pathway

BACKGROUND: PTPRU is an important signaling molecule that regulates a variety of cellular processes; however, the role of PTPRU in cancer development has remained elusive. Here, we report that PTPRU serves as a tumor suppressor that inhibits cancer stemness by attenuating Hippo/YAP signaling pathway...

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Detalles Bibliográficos
Autores principales: Gu, Jiayi, Zhang, Zhiqi, Lang, Tingyuan, Ma, Xinlin, Yang, Linxi, Xu, Jia, Tian, Cong, Han, Kun, Qiu, Jiangfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782031/
https://www.ncbi.nlm.nih.gov/pubmed/31632062
http://dx.doi.org/10.2147/OTT.S218125

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