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Long-term surviving influenza infected cells evade CD8(+) T cell mediated clearance

Influenza A virus (IAV) is a seasonal pathogen with the potential to cause devastating pandemics. IAV infects multiple epithelial cell subsets in the respiratory tract, eliciting damage to the lungs. Clearance of IAV is primarily dependent on CD8(+) T cells, which must balance control of the infecti...

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Detalles Bibliográficos
Autores principales: Fiege, Jessica K., Stone, Ian A., Dumm, Rebekah E., Waring, Barbara M., Fife, Brian T., Agudo, Judith, Brown, Brian D., Heaton, Nicholas S., Langlois, Ryan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782110/
https://www.ncbi.nlm.nih.gov/pubmed/31557273
http://dx.doi.org/10.1371/journal.ppat.1008077