An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone

Most known thioredoxin-type proteins (Trx) participate in redox pathways, using two highly conserved cysteine residues to catalyze thiol-disulfide exchange reactions. Here we demonstrate that the so far unexplored Trx2 from African trypanosomes (Trypanosoma brucei) lacks protein disulfide reductase...

Descripción completa

Detalles Bibliográficos
Autores principales: Currier, Rachel B., Ulrich, Kathrin, Leroux, Alejandro E., Dirdjaja, Natalie, Deambrosi, Matías, Bonilla, Mariana, Ahmed, Yasar Luqman, Adrian, Lorenz, Antelmann, Haike, Jakob, Ursula, Comini, Marcelo A., Krauth-Siegel, R. Luise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783113/
https://www.ncbi.nlm.nih.gov/pubmed/31557263
http://dx.doi.org/10.1371/journal.ppat.1008065

Ejemplares similares

Ejemplares similares