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N-acetyl cysteine inhibits lipopolysaccharide-mediated synthesis of interleukin-1β and tumor necrosis factor-α in human periodontal ligament fibroblast cells through nuclear factor-kappa B signaling

BACKGROUND: The aim of this study was to investigate the role of n-acetyl cysteine (NAC) in the lipopolysaccharide (LPS)-mediated induction of tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) synthesis by human periodontal ligament fibroblast cells (hPDLFs). In addition, we aimed to determ...

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Detalles Bibliográficos
Autores principales: Zheng, Rui, Tan, Yujie, Gu, Mengqin, Kang, Ting, Zhang, Hui, Guo, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783161/
https://www.ncbi.nlm.nih.gov/pubmed/31577702
http://dx.doi.org/10.1097/MD.0000000000017126