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Kinesin and dynein use distinct mechanisms to bypass obstacles

Kinesin-1 and cytoplasmic dynein are microtubule (MT) motors that transport intracellular cargoes. It remains unclear how these motors move along MTs densely coated with obstacles of various sizes in the cytoplasm. Here, we tested the ability of single and multiple motors to bypass synthetic obstacl...

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Detalles Bibliográficos
Autores principales: Ferro, Luke S, Can, Sinan, Turner, Meghan A, ElShenawy, Mohamed M, Yildiz, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783262/
https://www.ncbi.nlm.nih.gov/pubmed/31498080
http://dx.doi.org/10.7554/eLife.48629

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