Cryo-EM structure of the ClpXP protein degradation machinery

The ClpXP machinery is a two component protease complex performing targeted protein degradation in bacteria and mitochondria. The complex consists of the AAA+ chaperone ClpX and the peptidase ClpP. The hexameric ClpX utilizes the energy of ATP binding and hydrolysis to engage, unfold and translocate...

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Detalles Bibliográficos
Autores principales: Gatsogiannis, C, Balogh, D, Merino, F, Sieber, SA, Raunser, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783313/
https://www.ncbi.nlm.nih.gov/pubmed/31582852
http://dx.doi.org/10.1038/s41594-019-0304-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783313/
https://www.ncbi.nlm.nih.gov/pubmed/31582852
http://dx.doi.org/10.1038/s41594-019-0304-0

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