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Doc2b Ca(2+) binding site mutants enhance synaptic release at rest at the expense of sustained synaptic strength
Communication between neurons involves presynaptic neurotransmitter release which can be evoked by action potentials or occur spontaneously as a result of stochastic vesicle fusion. The Ca(2+)-binding double C(2) proteins Doc2a and –b were implicated in spontaneous and asynchronous evoked release, b...
Autores principales: | Bourgeois-Jaarsma, Quentin, Verhage, Matthijs, Groffen, Alexander J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783474/ https://www.ncbi.nlm.nih.gov/pubmed/31594980 http://dx.doi.org/10.1038/s41598-019-50684-1 |
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