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Fmr1-Deficiency Impacts Body Composition, Skeleton, and Bone Microstructure in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS) is a neurodevelopmental disorder associated with intellectual disability, hyperactivity, and autism. FXS is due to the silencing of the X-linked FMR1 gene. Murine models of FXS, knock-out (KO) for the murine homolog Fmr1, have been generated, exhibiting CNS-related behaviora...

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Detalles Bibliográficos
Autores principales: Leboucher, Antoine, Bermudez-Martin, Patricia, Mouska, Xavier, Amri, Ez-Zoubir, Pisani, Didier F., Davidovic, Laetitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783488/
https://www.ncbi.nlm.nih.gov/pubmed/31632352
http://dx.doi.org/10.3389/fendo.2019.00678

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