Cargando…

HBV cccDNA: The Stumbling Block for Treatment of HBV Infection

Detalles Bibliográficos
Autores principales:	Liu, Shousheng, Xin, Yongning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	XIA & HE Publishing Inc. 2019
Materias:	Editorial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783674/ https://www.ncbi.nlm.nih.gov/pubmed/31608210 http://dx.doi.org/10.14218/JCTH.2019.00047

Ejemplares similares

Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs
por: Li, Feng, et al.
Publicado: (2016)

The Role of cccDNA in HBV Maintenance
por: Allweiss, Lena, et al.
Publicado: (2017)

Mapping the Interactions of HBV cccDNA with Host Factors
por: Mohd-Ismail, Nur K., et al.
Publicado: (2019)

Gene Editing Technologies to Target HBV cccDNA
por: Martinez, Maria Guadalupe, et al.
Publicado: (2022)

HBV cccDNA and Its Potential as a Therapeutic Target
por: Zhu, Anjing, et al.
Publicado: (2019)

Reduced HBV cccDNA and HBsAg in HBV-associated hepatocellular carcinoma tissues
por: Tantiwetrueangdet, Anchalee, et al.
Publicado: (2018)

HBV cccDNA—A Culprit and Stumbling Block for the Hepatitis B Virus Infection: Its Presence in Hepatocytes Perplexed the Possible Mission for a Functional Cure
por: Bhat, Sajad Ahmad, et al.
Publicado: (2022)

Gene Therapy for Chronic HBV—Can We Eliminate cccDNA?
por: Bloom, Kristie, et al.
Publicado: (2018)

IFN-α confers epigenetic regulation of HBV cccDNA minichromosome by modulating GCN5-mediated succinylation of histone H3K79 to clear HBV cccDNA
por: Yuan, Ying, et al.
Publicado: (2020)

Dynamics of HBV cccDNA expression and transcription in different cell growth phase
por: Chong, Chin-Liew, et al.
Publicado: (2011)

Complete Spectrum of CRISPR/Cas9-induced Mutations on HBV cccDNA
por: Seeger, Christoph, et al.
Publicado: (2016)

HAT1 signaling confers to assembly and epigenetic regulation of HBV cccDNA minichromosome
por: Yang, Guang, et al.
Publicado: (2019)

cccDNA Surrogate MC-HBV–Based Screen Identifies Cohesin Complex as a Novel HBV Restriction Factor
por: Wu, Zhuanchang, et al.
Publicado: (2022)

Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target
por: Verrier, Eloi R, et al.
Publicado: (2023)

Serum HBV RNA correlated with intrahepatic cccDNA more strongly than other HBV markers during peg-interferon treatment
por: Wang, Xiaomei, et al.
Publicado: (2021)

IL6 Inhibits HBV Transcription by Targeting the Epigenetic Control of the Nuclear cccDNA Minichromosome
por: Palumbo, Gianna Aurora, et al.
Publicado: (2015)

Inhibition of HBV Transcription From cccDNA With Nitazoxanide by Targeting the HBx–DDB1 Interaction
por: Sekiba, Kazuma, et al.
Publicado: (2018)

Baseline value of intrahepatic HBV DNA over cccDNA predicts patient’s response to interferon therapy
por: Mu, Di, et al.
Publicado: (2017)

A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis
por: Wing, Peter AC, et al.
Publicado: (2019)

Correction: IL6 Inhibits HBV Transcription by Targeting the Epigenetic Control of the Nuclear cccDNA Minichromosome
por: Palumbo, Gianna Aurora, et al.
Publicado: (2015)

The recombined cccDNA produced using minicircle technology mimicked HBV genome in structure and function closely
por: Guo, Xiaoyan, et al.
Publicado: (2016)

Droplet digital PCR assay provides intrahepatic HBV cccDNA quantification tool for clinical application
por: Hayashi, Sanae, et al.
Publicado: (2022)

Reduction in Intrahepatic cccDNA and Integration of HBV in Chronic Hepatitis B Patients with a Functional Cure
por: Gan, Weiqiang, et al.
Publicado: (2023)

cccDNA-Targeted Drug Screen Reveals a Class of Antihistamines as Suppressors of HBV Genome Levels
por: Ren, Ee Chee, et al.
Publicado: (2023)

Cabozantinib inhibits HBV-RNA transcription by decreasing STAT3 binding to the enhancer region of cccDNA
por: Funato, Kazuyoshi, et al.
Publicado: (2023)

Molecular insights into Spindlin1-HBx interplay and its impact on HBV transcription from cccDNA minichromosome
por: Liu, Wei, et al.
Publicado: (2023)

Quantification of the hepatitis B virus cccDNA: evidence-based guidelines for monitoring the key obstacle of HBV cure
por: Allweiss, Lena, et al.
Publicado: (2023)

Evidence for long-term association of virion-delivered HBV core protein with cccDNA independently of viral protein production
por: Lucifora, Julie, et al.
Publicado: (2021)

Serum HBV DNA plus RNA reflecting cccDNA level before and during NAs treatment in HBeAg positive CHB patients
por: Wang, Yang, et al.
Publicado: (2022)

HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways
por: Guo, Fang, et al.
Publicado: (2017)

Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9
por: Kostyushev, Dmitry, et al.
Publicado: (2019)

Mechanism of Hepatitis B Virus cccDNA Formation
por: Wei, Lei, et al.
Publicado: (2021)

Estimating hepatitis B virus cccDNA persistence in chronic infection(†)
por: Lythgoe, Katrina A, et al.
Publicado: (2020)

Targeting Viral cccDNA for Cure of Chronic Hepatitis B
por: Ligat, Gaëtan, et al.
Publicado: (2020)

Yin-Yang 1 and HBx protein activate HBV transcription by mediating the spatial interaction of cccDNA minichromosome with cellular chromosome 19p13.11
por: Shen, Congle, et al.
Publicado: (2020)

A Stumbling Block
Publicado: (1879)

An Immortalized Hepatocyte-Like Cell Line (imHC) Accommodated Complete Viral Lifecycle, Viral Persistence Form, cccDNA and Eventual Spreading of a Clinically-Isolated HBV
por: Sa-ngiamsuntorn, Khanit, et al.
Publicado: (2019)

New biomarkers of hepatitis B virus (HBV) infection: HBV RNA and HBV core-related antigen, new kids on the block?
por: Lim, Young-Suk
Publicado: (2023)

Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus
por: Kitamura, Kouichi, et al.
Publicado: (2018)

cccDNA Maintenance in Chronic Hepatitis B – Targeting the Matrix of Viral Replication
por: Dandri, Maura, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qtpkpmhunlac2gcn02gh8rfo42