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Rational Design of an Orthogonal Pair of Bimolecular RNase P Ribozymes through Heterologous Assembly of Their Modular Domains

The modular structural domains of multidomain RNA enzymes can often be dissected into separate domain RNAs and their noncovalent assembly can often reconstitute active enzymes. These properties are important to understand their basic characteristics and are useful for their application to RNA-based...

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Detalles Bibliográficos
Autores principales:	Nozawa, Yuri, Hagihara, Megumi, Rahman, Md Sohanur, Matsumura, Shigeyoshi, Ikawa, Yoshiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783828/ https://www.ncbi.nlm.nih.gov/pubmed/31480450 http://dx.doi.org/10.3390/biology8030065

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