Chronic Low Dose Oral Exposure to Microcystin-LR Exacerbates Hepatic Injury in a Murine Model of Non-Alcoholic Fatty Liver Disease

Microcystins are potent hepatotoxins that have become a global health concern in recent years. Their actions in at-risk populations with pre-existing liver disease is unknown. We tested the hypothesis that the No Observed Adverse Effect Level (NOAEL) of Microcystin-LR (MC-LR) established in healthy...

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Detalles Bibliográficos
Autores principales: Lad, Apurva, Su, Robin C., Breidenbach, Joshua D., Stemmer, Paul M., Carruthers, Nicholas J., Sanchez, Nayeli K., Khalaf, Fatimah K., Zhang, Shungang, Kleinhenz, Andrew L., Dube, Prabhatchandra, Mohammed, Chrysan J., Westrick, Judy A., Crawford, Erin L., Palagama, Dilrukshika, Baliu-Rodriguez, David, Isailovic, Dragan, Levison, Bruce, Modyanov, Nikolai, Gohara, Amira F., Malhotra, Deepak, Haller, Steven T., Kennedy, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783870/
https://www.ncbi.nlm.nih.gov/pubmed/31450746
http://dx.doi.org/10.3390/toxins11090486

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