Establishment of a Parvovirus B19 NS1-Expressing Recombinant Adenoviral Vector for Killing Megakaryocytic Leukemia Cells

Adenoviral viral vectors have been widely used for gene-based therapeutics, but commonly used serotype 5 shows poor transduction efficiency into hematopoietic cells. In this study, we aimed to generate a recombinant adenovirus serotype 5 (rAd5) vector that has a high efficiency in gene transfer to m...

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Detalles Bibliográficos
Autores principales: Xu, Peng, Wang, Xiaomei, Li, Yi, Qiu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783920/
https://www.ncbi.nlm.nih.gov/pubmed/31487941
http://dx.doi.org/10.3390/v11090820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783920/
https://www.ncbi.nlm.nih.gov/pubmed/31487941
http://dx.doi.org/10.3390/v11090820

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