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Multifactorial Modeling Reveals a Dominant Role of Wnt Signaling in Lineage Commitment of Human Pluripotent Stem Cells

The human primed pluripotent state is maintained by a complex balance of several signaling pathways governing pluripotency maintenance and commitment. Here, we explore a multiparameter approach using a full factorial design and a simple well-defined culture system to assess individual and synergisti...

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Detalles Bibliográficos
Autores principales:	Dias, Tiago P., Fernandes, Tiago G., Diogo, Maria Margarida, Cabral, Joaquim M. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783940/ https://www.ncbi.nlm.nih.gov/pubmed/31443254 http://dx.doi.org/10.3390/bioengineering6030071

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