Synthesis of Ring II/III Fragment of Kanamycin: A New Minimum Structural Motif for Aminoglycoside Recognition

A novel protocol has been established to prepare the kanamycin ring II/III fragment, which has been validated as a minimum structural motif for the development of new aminoglycosides on the basis of its bactericidal activity even against resistant strains. Furthermore, its ability to act as a AAC-(6...

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Detalles Bibliográficos
Autores principales: Zárate, Sandra G., Bastida, Agatha, Santana, Andrés G., Revuelta, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783941/
https://www.ncbi.nlm.nih.gov/pubmed/31382490
http://dx.doi.org/10.3390/antibiotics8030109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783941/
https://www.ncbi.nlm.nih.gov/pubmed/31382490
http://dx.doi.org/10.3390/antibiotics8030109

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