NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors

NKAP is a multi-functional nuclear protein that has been shown to be essential for hematopoiesis. Deletion of NKAP in hematopoietic stem cells (HSCs) was previously found to result in rapid lethality and hematopoietic failure. NKAP deficient cells also exhibited diminished proliferation and increase...

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Detalles Bibliográficos
Autores principales: Shapiro, Michael Jeremy, Anderson, Joshua, Lehrke, Michael Jonathan, Chen, Meibo, Nelson Holte, Molly, Shapiro, Virginia Smith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783958/
https://www.ncbi.nlm.nih.gov/pubmed/31632967
http://dx.doi.org/10.3389/fcell.2019.00214

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