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Temozolomide and Other Alkylating Agents in Glioblastoma Therapy

The alkylating agent temozolomide (TMZ) together with maximal safe bulk resection and focal radiotherapy comprises the standard treatment for glioblastoma (GB), a particularly aggressive and lethal primary brain tumor. GB affects 3.2 in 100,000 people who have an average survival time of around 14 m...

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Detalles Bibliográficos
Autores principales:	Strobel, Hannah, Baisch, Tim, Fitzel, Rahel, Schilberg, Katharina, Siegelin, Markus D., Karpel-Massler, Georg, Debatin, Klaus-Michael, Westhoff, Mike-Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783999/ https://www.ncbi.nlm.nih.gov/pubmed/31505812 http://dx.doi.org/10.3390/biomedicines7030069

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