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MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors
The detection of drug resistance mutations (DRMs) in minor viral populations is of potential clinical importance. However, sophisticated computational infrastructure and competence for analysis of high-throughput sequencing (HTS) data lack at most diagnostic laboratories. Thus, we have proposed a ne...
Autores principales: | Aralaguppe, Shambhu G., Ambikan, Anoop T., Ashokkumar, Manickam, Kumar, Milner M., Hanna, Luke Elizabeth, Amogne, Wondwossen, Sönnerborg, Anders, Neogi, Ujjwal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784143/ https://www.ncbi.nlm.nih.gov/pubmed/31480341 http://dx.doi.org/10.3390/v11090806 |
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