Throw out the Map: Neuropathogenesis of the Globally Expanding California Serogroup of Orthobunyaviruses

The California serogroup (CSG) comprises 18 serologically and genetically related mosquito-borne orthobunyaviruses. Of these viruses, at least seven have been shown to cause neurological disease in humans, including the leading cause of pediatric arboviral encephalitis in the USA, La Crosse virus. D...

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Autores principales: Evans, Alyssa B., Peterson, Karin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784171/
https://www.ncbi.nlm.nih.gov/pubmed/31470541
http://dx.doi.org/10.3390/v11090794
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author Evans, Alyssa B.
Peterson, Karin E.
author_facet Evans, Alyssa B.
Peterson, Karin E.
author_sort Evans, Alyssa B.
collection PubMed
description The California serogroup (CSG) comprises 18 serologically and genetically related mosquito-borne orthobunyaviruses. Of these viruses, at least seven have been shown to cause neurological disease in humans, including the leading cause of pediatric arboviral encephalitis in the USA, La Crosse virus. Despite the disease burden from these viruses, much is still unknown about the CSG viruses. This review summarizes our current knowledge of the CSG viruses, including human disease and the mechanisms of neuropathogenesis.
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spelling pubmed-67841712019-10-16 Throw out the Map: Neuropathogenesis of the Globally Expanding California Serogroup of Orthobunyaviruses Evans, Alyssa B. Peterson, Karin E. Viruses Review The California serogroup (CSG) comprises 18 serologically and genetically related mosquito-borne orthobunyaviruses. Of these viruses, at least seven have been shown to cause neurological disease in humans, including the leading cause of pediatric arboviral encephalitis in the USA, La Crosse virus. Despite the disease burden from these viruses, much is still unknown about the CSG viruses. This review summarizes our current knowledge of the CSG viruses, including human disease and the mechanisms of neuropathogenesis. MDPI 2019-08-29 /pmc/articles/PMC6784171/ /pubmed/31470541 http://dx.doi.org/10.3390/v11090794 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Evans, Alyssa B.
Peterson, Karin E.
Throw out the Map: Neuropathogenesis of the Globally Expanding California Serogroup of Orthobunyaviruses
title Throw out the Map: Neuropathogenesis of the Globally Expanding California Serogroup of Orthobunyaviruses
title_full Throw out the Map: Neuropathogenesis of the Globally Expanding California Serogroup of Orthobunyaviruses
title_fullStr Throw out the Map: Neuropathogenesis of the Globally Expanding California Serogroup of Orthobunyaviruses
title_full_unstemmed Throw out the Map: Neuropathogenesis of the Globally Expanding California Serogroup of Orthobunyaviruses
title_short Throw out the Map: Neuropathogenesis of the Globally Expanding California Serogroup of Orthobunyaviruses
title_sort throw out the map: neuropathogenesis of the globally expanding california serogroup of orthobunyaviruses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784171/
https://www.ncbi.nlm.nih.gov/pubmed/31470541
http://dx.doi.org/10.3390/v11090794
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