Cargando…

Insights into Thymus Development and Viral Thymic Infections

T-cell development in the thymus is a complex and highly regulated process, involving a wide variety of cells and molecules which orchestrate thymocyte maturation into either CD4(+) or CD8(+) single-positive (SP) T cells. Here, we briefly review the process regulating T-cell differentiation, which i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Albano, Francesco, Vecchio, Eleonora, Renna, Maurizio, Iaccino, Enrico, Mimmi, Selena, Caiazza, Carmen, Arcucci, Alessandro, Avagliano, Angelica, Pagliara, Valentina, Donato, Giuseppe, Palmieri, Camillo, Mallardo, Massimo, Quinto, Ileana, Fiume, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784209/ https://www.ncbi.nlm.nih.gov/pubmed/31505755 http://dx.doi.org/10.3390/v11090836

Ejemplares similares

IBtkα Activates the β-Catenin-Dependent Transcription of MYC through Ubiquitylation and Proteasomal Degradation of GSK3β in Cancerous B Cells
por: Vecchio, Eleonora, et al.
Publicado: (2022)

Metabolites Profiling of Melanoma Interstitial Fluids Reveals Uridine Diphosphate as Potent Immune Modulator Capable of Limiting Tumor Growth
por: Vecchio, Eleonora, et al.
Publicado: (2021)

Role of Chronic Lymphocytic Leukemia (CLL)-Derived Exosomes in Tumor Progression and Survival
por: Nisticò, Nancy, et al.
Publicado: (2020)

IBTK Haploinsufficiency Affects the Tumor Microenvironment of Myc-Driven Lymphoma in E-myc Mice
por: Vecchio, Eleonora, et al.
Publicado: (2020)

Phage-Displayed Peptides for Targeting Tyrosine Kinase Membrane Receptors in Cancer Therapy
por: Aloisio, Annamaria, et al.
Publicado: (2021)

The expression of inhibitor of bruton’s tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis
por: Albano, Francesco, et al.
Publicado: (2018)

Insights about MYC and Apoptosis in B-Lymphomagenesis: An Update from Murine Models
por: Vecchio, Eleonora, et al.
Publicado: (2020)

Uncovering the Exosomes Diversity: A Window of Opportunity for Tumor Progression Monitoring
por: Maisano, Domenico, et al.
Publicado: (2020)

IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis
por: Vecchio, Eleonora, et al.
Publicado: (2019)

Revisiting Bacterial Ubiquitin Ligase Effectors: Weapons for Host Exploitation
por: Pisano, Antonio, et al.
Publicado: (2018)

Detection of chronic lymphocytic leukemia subpopulations in peripheral blood by phage ligands of tumor immunoglobulin B cell receptors
por: Mimmi, Selena, et al.
Publicado: (2020)

IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells
por: Fiume, Giuseppe, et al.
Publicado: (2016)

The Lack of STING Impairs the MHC-I Dependent Antigen Presentation and JAK/STAT Signaling in Murine Macrophages
por: Caiazza, Carmen, et al.
Publicado: (2022)

Monitoring multiple myeloma by idiotype-specific peptide binders of tumor-derived exosomes
por: Iaccino, Enrico, et al.
Publicado: (2017)

CRL3(IBTK) Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation
por: Pisano, Antonio, et al.
Publicado: (2015)

Unmutated IGHV1-69 CLL Clone Displays a Distinct Gene Expression Profile by a Comparative qRT-PCR Assay
por: Mimmi, Selena, et al.
Publicado: (2022)

Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB
por: Fiume, Giuseppe, et al.
Publicado: (2013)

Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice
por: Fiume, Giuseppe, et al.
Publicado: (2015)

Predominant VH1-69 IgBCR Clones Show Higher Expression of CD5 in Heterogeneous Chronic Lymphocytic Leukemia Populations
por: Maisano, Domenico, et al.
Publicado: (2021)

The aftermath of the Merck's HIV vaccine trial
por: Iaccino, Enrico, et al.
Publicado: (2008)

Inhibition of HIV-1 replication in primary human monocytes by the IκB-αS32/36A repressor of NF-κB
por: Palmieri, Camillo, et al.
Publicado: (2004)

Peptide-guided targeting of GPR55 for anti-cancer therapy
por: Mangini, Maria, et al.
Publicado: (2016)

Thyroid Cancer and Fibroblasts
por: Avagliano, Angelica, et al.
Publicado: (2022)

Influence of Fibroblasts on Mammary Gland Development, Breast Cancer Microenvironment Remodeling, and Cancer Cell Dissemination
por: Avagliano, Angelica, et al.
Publicado: (2020)

Evidence of shared epitopic reactivity among independent B-cell clones in chronic lymphocytic leukemia patients
por: Mimmi, S, et al.
Publicado: (2016)

Design and Characterization of a Peptide Mimotope of the HIV-1 gp120 Bridging Sheet
por: Schiavone, Marco, et al.
Publicado: (2012)

Metabolic Plasticity of Melanoma Cells and Their Crosstalk With Tumor Microenvironment
por: Avagliano, Angelica, et al.
Publicado: (2020)

Human immunodeficiency virus-1 Tat activates NF-κB via physical interaction with IκB-α and p65
por: Fiume, Giuseppe, et al.
Publicado: (2012)

Development of Cyclic Peptides Targeting the Epidermal Growth Factor Receptor in Mesenchymal Triple-Negative Breast Cancer Subtype
por: Nisticò, Nancy, et al.
Publicado: (2023)

B-cell receptor-guided delivery of peptide-siRNA complex for B-cell lymphoma therapy
por: Migliaccio, Nunzia, et al.
Publicado: (2015)

Influence of Tumor Microenvironment and Fibroblast Population Plasticity on Melanoma Growth, Therapy Resistance and Immunoescape
por: Romano, Veronica, et al.
Publicado: (2021)

Editorial: Lymphoid cells and tumor microenvironment: a functional crosstalk
por: Mimmi, Selena, et al.
Publicado: (2023)

Aberrant Glycosylation as Biomarker for Cancer: Focus on CD43
por: Tuccillo, Franca Maria, et al.
Publicado: (2014)

Generation and analysis of spheroids from human primary skin myofibroblasts: an experimental system to study myofibroblasts deactivation
por: Granato, Giuseppina, et al.
Publicado: (2017)

Molecular T-Cell Repertoire Analysis as Source of Prognostic and Predictive Biomarkers for Checkpoint Blockade Immunotherapy
por: Aversa, Ilenia, et al.
Publicado: (2020)

Positive and Negative Selection in the Thymus and the Thymic Paradox
por: Reza, Julie N., et al.
Publicado: (1998)

Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts
por: Avagliano, Angelica, et al.
Publicado: (2019)

STUDIES ON THYMUS FUNCTION : III. DURATION OF THYMIC FUNCTION
por: Stutman, Osias, et al.
Publicado: (1972)

Tbata modulates thymic stromal cell proliferation and thymus function
por: Flomerfelt, Francis A., et al.
Publicado: (2010)

Editorial: Tumor Microenvironment and Cancer Cell Interactions in Solid Tumor Growth and Therapy Resistance
por: Ruocco, Maria Rosaria, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p6vnjb0a4e71gjukeq0ivbr20e