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Mitochondrial Toxicity of Azithromycin Results in Aerobic Glycolysis and DNA Damage of Human Mammary Epithelia and Fibroblasts

Mitochondria evolved from free-living bacteria via endocytosis within eukaryotic host cells millions of year ago. We hypothesized that antibiotics cause mammalian mitochondrial damage while causing bacterial lethality. Mitochondrial toxicity of azithromycin in human mammary epithelia MCF-12A and fib...

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Detalles Bibliográficos
Autores principales: Jiang, Xianpeng, Baucom, Catherine, Elliott, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784251/
https://www.ncbi.nlm.nih.gov/pubmed/31382608
http://dx.doi.org/10.3390/antibiotics8030110

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