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Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children
BACKGROUND: Despite improved diagnostics, pulmonary pathogens in immunocompromised children frequently evade detection, leading to significant mortality. Therefore, we aimed to develop a highly sensitive metagenomic next-generation sequencing (mNGS) assay capable of evaluating the pulmonary microbio...
Autores principales: | Zinter, Matt S, Dvorak, Christopher C, Mayday, Madeline Y, Iwanaga, Kensho, Ly, Ngoc P, McGarry, Meghan E, Church, Gwynne D, Faricy, Lauren E, Rowan, Courtney M, Hume, Janet R, Steiner, Marie E, Crawford, Emily D, Langelier, Charles, Kalantar, Katrina, Chow, Eric D, Miller, Steve, Shimano, Kristen, Melton, Alexis, Yanik, Gregory A, Sapru, Anil, DeRisi, Joseph L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784263/ https://www.ncbi.nlm.nih.gov/pubmed/30239621 http://dx.doi.org/10.1093/cid/ciy802 |
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