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Driver mutations in USP8 wild-type Cushing’s disease

BACKGROUND: Medical treatment in Cushing’s disease (CD) is limited due to poor understanding of its pathogenesis. Pathogenic variants of ubiquitin specific peptidase 8 (USP8) have been confirmed as causative in around half of corticotroph tumors. We aimed to further characterize the molecular landsc...

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Detalles Bibliográficos
Autores principales:	Sbiera, Silviu, Perez-Rivas, Luis Gustavo, Taranets, Lyudmyla, Weigand, Isabel, Flitsch, Jörg, Graf, Elisabeth, Monoranu, Camelia-Maria, Saeger, Wolfgang, Hagel, Christian, Honegger, Jürgen, Assie, Guillaume, Hermus, Ad R, Stalla, Günter K, Herterich, Sabine, Ronchi, Cristina L, Deutschbein, Timo, Reincke, Martin, Strom, Tim M, Popov, Nikita, Theodoropoulou, Marily, Fassnacht, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784271/ https://www.ncbi.nlm.nih.gov/pubmed/31222332 http://dx.doi.org/10.1093/neuonc/noz109

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