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Development of a Label-Free Electrochemical Aptasensor for the Detection of Tau381 and its Preliminary Application in AD and Non-AD Patients’ Sera

The electrochemical aptamer sensor has been designed for detecting tau381, a critical biomarker of Alzheimer′s disease in human serum. The aptasensor is obtained by immobilizing the aptamer on a carboxyl graphene/thionin/gold nanoparticle modified glassy-carbon electrode. As a probe and bridge molec...

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Detalles Bibliográficos
Autores principales:	Tao, Dan, Shui, Bingqing, Gu, Yingying, Cheng, Jing, Zhang, Weiying, Jaffrezic-Renault, Nicole, Song, Shizhen, Guo, Zhenzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784373/ https://www.ncbi.nlm.nih.gov/pubmed/31262001 http://dx.doi.org/10.3390/bios9030084

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