Approach to Strain Selection and the Propagation of Viral Stocks for Venezuelan Equine Encephalitis Virus Vaccine Efficacy Testing under the Animal Rule

Licensure of a vaccine to protect against aerosolized Venezuelan equine encephalitis virus (VEEV) requires use of the U.S. Food and Drug Administration (FDA) Animal Rule to assess vaccine efficacy as human studies are not feasible or ethical. An approach to selecting VEEV challenge strains for use u...

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Detalles Bibliográficos
Autores principales: Rusnak, Janice M., Glass, Pamela J., Weaver, Scott C., Sabourin, Carol L., Glenn, Andrew M., Klimstra, William, Badorrek, Christopher S., Nasar, Farooq, Ward, Lucy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784384/
https://www.ncbi.nlm.nih.gov/pubmed/31480472
http://dx.doi.org/10.3390/v11090807

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