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Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017

BACKGROUND: Respiratory syncytial virus (RSV) is a major contributor to lower respiratory tract infections worldwide and several vaccine candidates are currently in development. Following vaccine introduction, reliable RSV surveillance should enable monitoring of vaccination impact. Data on the RSV...

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Autores principales: Mollers, Madelief, Barnadas, Céline, Broberg, Eeva K, Penttinen, Pasi, Teirlinck, Anne C, Fischer, Thea K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784450/
https://www.ncbi.nlm.nih.gov/pubmed/31595876
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.40.1900157
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author Mollers, Madelief
Barnadas, Céline
Broberg, Eeva K
Penttinen, Pasi
Teirlinck, Anne C
Fischer, Thea K
author_facet Mollers, Madelief
Barnadas, Céline
Broberg, Eeva K
Penttinen, Pasi
Teirlinck, Anne C
Fischer, Thea K
author_sort Mollers, Madelief
collection PubMed
description BACKGROUND: Respiratory syncytial virus (RSV) is a major contributor to lower respiratory tract infections worldwide and several vaccine candidates are currently in development. Following vaccine introduction, reliable RSV surveillance should enable monitoring of vaccination impact. Data on the RSV disease burden in the European Union and European Economic Area (EU/EEA) are sparse. AIM: The aim of this study was to gather knowledge on current practices of national RSV surveillance in the EU/EEA. METHODS: National Coordinators and National Focal Points for Influenza (epidemiologists and virologists) from the EU/EEA countries (n = 31) were invited to participate in an online survey in August and September 2017. The questionnaire covered questions on epidemiological and laboratory aspects of RSV surveillance. RESULTS: All EU/EEA countries except Liechtenstein replied to the survey. Eighteen countries reported to have a sentinel surveillance system, 26 countries a non-sentinel surveillance system and three countries to have neither. RSV data collection was mostly done within the context of influenza surveillance. A wide range of diagnostic and characterisation assays was used for the detection of RSV. DISCUSSION: The majority of EU/EEA countries have some surveillance for RSV in place. The prevailing integration of RSV surveillance into the existing influenza sentinel surveillance system may lead to under-reporting of RSV. The documented variations in existing RSV surveillance systems and their outputs indicate that there is scope for developing guidelines on establishing comparable methods and outcomes for RSV surveillance across the EU/EEA, to ensure the availability of a consistent evidence base for assessing future vaccination programmes.
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spelling pubmed-67844502019-10-18 Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017 Mollers, Madelief Barnadas, Céline Broberg, Eeva K Penttinen, Pasi Teirlinck, Anne C Fischer, Thea K Euro Surveill Research BACKGROUND: Respiratory syncytial virus (RSV) is a major contributor to lower respiratory tract infections worldwide and several vaccine candidates are currently in development. Following vaccine introduction, reliable RSV surveillance should enable monitoring of vaccination impact. Data on the RSV disease burden in the European Union and European Economic Area (EU/EEA) are sparse. AIM: The aim of this study was to gather knowledge on current practices of national RSV surveillance in the EU/EEA. METHODS: National Coordinators and National Focal Points for Influenza (epidemiologists and virologists) from the EU/EEA countries (n = 31) were invited to participate in an online survey in August and September 2017. The questionnaire covered questions on epidemiological and laboratory aspects of RSV surveillance. RESULTS: All EU/EEA countries except Liechtenstein replied to the survey. Eighteen countries reported to have a sentinel surveillance system, 26 countries a non-sentinel surveillance system and three countries to have neither. RSV data collection was mostly done within the context of influenza surveillance. A wide range of diagnostic and characterisation assays was used for the detection of RSV. DISCUSSION: The majority of EU/EEA countries have some surveillance for RSV in place. The prevailing integration of RSV surveillance into the existing influenza sentinel surveillance system may lead to under-reporting of RSV. The documented variations in existing RSV surveillance systems and their outputs indicate that there is scope for developing guidelines on establishing comparable methods and outcomes for RSV surveillance across the EU/EEA, to ensure the availability of a consistent evidence base for assessing future vaccination programmes. European Centre for Disease Prevention and Control (ECDC) 2019-10-03 /pmc/articles/PMC6784450/ /pubmed/31595876 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.40.1900157 Text en This article is copyright of the authors or their affiliated institutions, 2019. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Research
Mollers, Madelief
Barnadas, Céline
Broberg, Eeva K
Penttinen, Pasi
Teirlinck, Anne C
Fischer, Thea K
Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017
title Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017
title_full Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017
title_fullStr Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017
title_full_unstemmed Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017
title_short Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017
title_sort current practices for respiratory syncytial virus surveillance across the eu/eea member states, 2017
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784450/
https://www.ncbi.nlm.nih.gov/pubmed/31595876
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.40.1900157
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