Wild-type p53-induced phosphatase 1 promotes vascular smooth muscle cell proliferation and neointima hyperplasia after vascular injury via p-adenosine 5′-monophosphate-activated protein kinase/mammalian target of rapamycin complex 1 pathway

Vascular smooth muscle cell (VSMC) proliferation is a crucial cause of vascular neointima hyperplasia and restenosis, thus limiting the long-term efficacy of percutaneous vascular intervention. We explored the role of wild-type p53-induced phosphatase 1 (Wip1), a potent regulator of tumorigenesis an...

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Detalles Bibliográficos
Autores principales: Sun, Xiongshan, Li, Shuang, Gan, Xueqing, Qiu, Chenming, Chen, Ken, Pei, Haifeng, Wang, Qiang, Li, De, Li, Xiuchuan, Yang, Dachun, Yang, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
ORIGINAL PAPERS: Organ damage
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784764/
https://www.ncbi.nlm.nih.gov/pubmed/31136458
http://dx.doi.org/10.1097/HJH.0000000000002159

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