The Carcinogenome Project: In Vitro Gene Expression Profiling of Chemical Perturbations to Predict Long-Term Carcinogenicity

BACKGROUND: Most chemicals in commerce have not been evaluated for their carcinogenic potential. The de facto gold-standard approach to carcinogen testing adopts the 2-y rodent bioassay, a time-consuming and costly procedure. High-throughput in vitro assays are a promising alternative for addressing...

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Detalles Bibliográficos
Autores principales: Li, Amy, Lu, Xiaodong, Natoli, Ted, Bittker, Joshua, Sipes, Nisha S., Subramanian, Aravind, Auerbach, Scott, Sherr, David H., Monti, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785232/
https://www.ncbi.nlm.nih.gov/pubmed/30964323
http://dx.doi.org/10.1289/EHP3986

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