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Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across
BACKGROUND: Low-cost, high-throughput in vitro bioassays have potential as alternatives to animal models for toxicity testing. However, incorporating in vitro bioassays into chemical toxicity evaluations such as read-across requires significant data curation and analysis based on knowledge of releva...
Autores principales: | Russo, Daniel P., Strickland, Judy, Karmaus, Agnes L., Wang, Wenyi, Shende, Sunil, Hartung, Thomas, Aleksunes, Lauren M., Zhu, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785238/ https://www.ncbi.nlm.nih.gov/pubmed/30933541 http://dx.doi.org/10.1289/EHP3614 |
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