Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway

Alternative lengthening of telomeres (ALT) is known to use homologous recombination (HR) to replicate telomeric DNA in a telomerase-independent manner. However, the detailed process remains largely undefined. It was reported that nuclear receptors COUP-TFII and TR4 are recruited to the enriched GGGT...

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Detalles Bibliográficos
Autores principales: Xu, Mafei, Qin, Jun, Wang, Leiming, Lee, Hui-Ju, Kao, Chung-Yang, Liu, Dan, Songyang, Zhou, Chen, Junjie, Tsai, Ming-Jer, Tsai, Sophia Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785246/
https://www.ncbi.nlm.nih.gov/pubmed/31633027
http://dx.doi.org/10.1126/sciadv.aax6366

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