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Analysis of “old” proteins unmasks dynamic gradient of cartilage turnover in human limbs
Unlike highly regenerative animals, such as axolotls, humans are believed to be unable to counteract cumulative damage, such as repetitive joint use and injury that lead to the breakdown of cartilage and the development of osteoarthritis. Turnover of insoluble collagen has been suggested to be very...
Autores principales: | Hsueh, Ming-Feng, Önnerfjord, Patrik, Bolognesi, Michael P., Easley, Mark E., Kraus, Virginia B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785252/ https://www.ncbi.nlm.nih.gov/pubmed/31633025 http://dx.doi.org/10.1126/sciadv.aax3203 |
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