Cargando…
Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells
The urothelium is an epithelial barrier lining the bladder that protects against infection, fluid exchange and damage from toxins. The nuclear receptor Pparg promotes urothelial differentiation in vitro, and Pparg mutations are associated with bladder cancer. However, the function of Pparg in the he...
Autores principales: | Liu, Chang, Tate, Tiffany, Batourina, Ekatherina, Truschel, Steven T., Potter, Steven, Adam, Mike, Xiang, Tina, Picard, Martin, Reiley, Maia, Schneider, Kerry, Tamargo, Manuel, Lu, Chao, Chen, Xiao, He, Jing, Kim, Hyunwoo, Mendelsohn, Cathy Lee |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785552/ https://www.ncbi.nlm.nih.gov/pubmed/31597917 http://dx.doi.org/10.1038/s41467-019-12332-0 |
Ejemplares similares
-
Pparg signaling controls bladder cancer subtype and immune exclusion
por: Tate, Tiffany, et al.
Publicado: (2021) -
Gardnerella Exposures Alter Bladder Gene Expression and Augment Uropathogenic Escherichia coli Urinary Tract Infection in Mice
por: Gilbert, Nicole M., et al.
Publicado: (2022) -
Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication
por: Wang, Jia, et al.
Publicado: (2018) -
Stromal Protein Ecm1 Regulates Ureteric Bud Patterning and Branching
por: Paroly, Suneeta S., et al.
Publicado: (2013) -
The Genetics of PPARG and the Skeleton
por: Ackert-Bicknell, Cheryl, et al.
Publicado: (2006)