Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship

Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4–9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis coul...

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Detalles Bibliográficos
Autores principales: Lockhart, Gabriel C, Hanin, Jacob, Micek, Scott T, Kollef, Marin H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785674/
https://www.ncbi.nlm.nih.gov/pubmed/31660359
http://dx.doi.org/10.1093/ofid/ofz397
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author Lockhart, Gabriel C
Hanin, Jacob
Micek, Scott T
Kollef, Marin H
author_facet Lockhart, Gabriel C
Hanin, Jacob
Micek, Scott T
Kollef, Marin H
author_sort Lockhart, Gabriel C
collection PubMed
description Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4–9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis could represent an important opportunity for antimicrobial stewardship.
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spelling pubmed-67856742019-10-15 Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship Lockhart, Gabriel C Hanin, Jacob Micek, Scott T Kollef, Marin H Open Forum Infect Dis Brief Report Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4–9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis could represent an important opportunity for antimicrobial stewardship. Oxford University Press 2019-10-09 /pmc/articles/PMC6785674/ /pubmed/31660359 http://dx.doi.org/10.1093/ofid/ofz397 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Lockhart, Gabriel C
Hanin, Jacob
Micek, Scott T
Kollef, Marin H
Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship
title Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship
title_full Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship
title_fullStr Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship
title_full_unstemmed Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship
title_short Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship
title_sort pathogen-negative sepsis—an opportunity for antimicrobial stewardship
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785674/
https://www.ncbi.nlm.nih.gov/pubmed/31660359
http://dx.doi.org/10.1093/ofid/ofz397
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AT micekscottt pathogennegativesepsisanopportunityforantimicrobialstewardship
AT kollefmarinh pathogennegativesepsisanopportunityforantimicrobialstewardship

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