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Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells

Accumulation of senescent endothelial cells can cause endothelium dysfunction which eventually leads to age-related vascular disorders. The senescent-associated secretory phenotype (SASP) cells secrete a plethora of soluble factors that negatively influence the surrounding tissue microenvironment. T...

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Detalles Bibliográficos
Autores principales:	Wong, Pooi-Fong, Tong, Kind-Leng, Jamal, Juliana, Khor, Eng-Soon, Lai, Siew-Li, Mustafa, Mohd Rais
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785768/ https://www.ncbi.nlm.nih.gov/pubmed/31611757 http://dx.doi.org/10.17179/excli2019-1505

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