Efficacy of Typhoid Conjugate Vaccine in Nepal: An Interim Analysis of a Participant-and Observer-Blinded Randomized Phase III Trial

BACKGROUND: Salmonella Typhi is a major cause of fever in children in low- and middle-income countries. The recently WHO prequalified typhoid conjugate vaccine (TCV) was shown to be efficacious in a human challenge model but no efficacy trials in endemic populations have been completed. METHODS: In...

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Detalles Bibliográficos
Autores principales: Shakya, Mila, Colin-Jones, Rachel, Theiss-Nyland, Katherine, Voysey, Merryn, Pant, Dikshya, Smith, Nicola, Liu, Xinxue, Tonks, Susan, Mazur, Olga, Farooq, Yama G., Clarke, Jenny, Hill, Jennifer, Adhikari, Anup, Dongol, Sabina, Karkey, Abhilasha, Bajracharya, Binod, Kelly, Sarah, Gurung, Meeru, Baker, Stephen, Neuzil, Kathleen M., Shrestha, Shrijana, Basnyat, Buddha, Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785806/
https://www.ncbi.nlm.nih.gov/pubmed/31800986
http://dx.doi.org/10.1056/NEJMoa1905047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785806/
https://www.ncbi.nlm.nih.gov/pubmed/31800986
http://dx.doi.org/10.1056/NEJMoa1905047

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