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Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-Resistant Pseudomonas aeruginosa

Polymyxins are used as a last-resort class of antibiotics against multidrug-resistant (MDR) Gram-negative Pseudomonas aeruginosa. As polymyxin monotherapy is associated with potential development of resistance, combination therapy is highly recommended. This study investigated the mechanism underlyi...

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Detalles Bibliográficos
Autores principales:	Lin, Yu-Wei, Han, Mei-Ling, Zhao, Jinxin, Zhu, Yan, Rao, Gauri, Forrest, Alan, Song, Jiangning, Kaye, Keith S., Hertzog, Paul, Purcell, Anthony, Creek, Darren, Zhou, Qi Tony, Velkov, Tony, Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785843/ https://www.ncbi.nlm.nih.gov/pubmed/31632279 http://dx.doi.org/10.3389/fphar.2019.01146

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