LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma

BACKGROUND: PVT1 has emerged as an oncogene in many tumor types. However, its role in Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) is unknown. The aim of this study was to assess the role of PVT1 in BE/EAC progression and uncover its therapeutic value against EAC. METHODS: PVT1 expre...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Li, Yuan, Jin, Jiankang, Han, Guangchun, Sun, Chengcao, Pizzi, Melissa Pool, Huo, Longfei, Scott, Ailing, Wang, Ying, Ma, Lang, Lee, Jeffrey H., Bhutani, Manoop S., Weston, Brian, Vellano, Christopher, Yang, Liuqing, Lin, Chunru, Kim, Youngsoo, MacLeod, A. Robert, Wang, Linghua, Wang, Zhenning, Song, Shumei, Ajani, Jaffer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785865/
https://www.ncbi.nlm.nih.gov/pubmed/31601234
http://dx.doi.org/10.1186/s12943-019-1064-5

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