Bovine ephemeral fever virus triggers autophagy enhancing virus replication via upregulation of the Src/JNK/AP1 and PI3K/Akt/NF-κB pathways and suppression of the PI3K/Akt/mTOR pathway

Autophagy plays an important role in cellular response to pathogens. However, the impact of the autophagy machinery on bovine ephemeral fever virus (BEFV) infection is not yet determined. A recent study in our laboratory demonstrated that BEFV triggers simultaneously the PI3K/Akt/NF-κB and Src/JNK-A...

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Detalles Bibliográficos
Autores principales: Cheng, Ching-Yuan, Tseng, Hsu-Hung, Chiu, Hung-Chuan, Chang, Ching-Dong, Nielsen, Brent L., Liu, Hung-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785866/
https://www.ncbi.nlm.nih.gov/pubmed/31601269
http://dx.doi.org/10.1186/s13567-019-0697-0

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