Targeting Inflammatory Processes Mediated by TRPVI and TNF-α for Treating Noise-Induced Hearing Loss

Noise trauma is the most common cause of hearing loss in adults. There are no known FDA approved drugs for prevention or rescue of noise-induced hearing loss (NIHL). In this study, we provide evidence that implicates stress signaling molecules (TRPV1, NOX3, and TNF-α) in NIHL. Furthermore, we provid...

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Detalles Bibliográficos
Autores principales: Dhukhwa, Asmita, Bhatta, Puspanjali, Sheth, Sandeep, Korrapati, Krishi, Tieu, Coral, Mamillapalli, Chaitanya, Ramkumar, Vickram, Mukherjea, Debashree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786284/
https://www.ncbi.nlm.nih.gov/pubmed/31632242
http://dx.doi.org/10.3389/fncel.2019.00444

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