Cargando…

Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study

The aim of our study was to compare early and long-term outcome of patients undergoing either on-pump or off-pump coronary artery bypass grafting with special focus on impairment of renal function. Five hundred ninety-three consecutive patients undergoing coronary artery bypass grafting were retrosp...

Descripción completa

Detalles Bibliográficos
Autores principales: Merkle, Julia, Sunny, Jaison, Ehlscheid, Laura, Sabashnikov, Anton, Weber, Carolyn, Eghbalzadeh, Kaveh, Djordjevic, Ilija, Liakopoulos, Oliver, Choi, Yeong-Hoon, Wahlers, Thorsten, Zeriouh, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786630/
https://www.ncbi.nlm.nih.gov/pubmed/31600308
http://dx.doi.org/10.1371/journal.pone.0223806
_version_ 1783458103720673280
author Merkle, Julia
Sunny, Jaison
Ehlscheid, Laura
Sabashnikov, Anton
Weber, Carolyn
Eghbalzadeh, Kaveh
Djordjevic, Ilija
Liakopoulos, Oliver
Choi, Yeong-Hoon
Wahlers, Thorsten
Zeriouh, Mohamed
author_facet Merkle, Julia
Sunny, Jaison
Ehlscheid, Laura
Sabashnikov, Anton
Weber, Carolyn
Eghbalzadeh, Kaveh
Djordjevic, Ilija
Liakopoulos, Oliver
Choi, Yeong-Hoon
Wahlers, Thorsten
Zeriouh, Mohamed
author_sort Merkle, Julia
collection PubMed
description The aim of our study was to compare early and long-term outcome of patients undergoing either on-pump or off-pump coronary artery bypass grafting with special focus on impairment of renal function. Five hundred ninety-three consecutive patients undergoing coronary artery bypass grafting were retrospectively analyzed. They were assigned either to on-pump (n = 281) or to off-pump (n = 312) group. Early and long-term outcomes were analyzed with special focus on renal function. Basic demographics and preoperative characteristics did not differ between groups (p>0.05) as well as postoperative renal parameters (p>0.05). Postoperative odds ratios (OR) of off-pump group in comparison to on-pump group were higher without reaching significance in terms of incidence of gastrointestinal complications and pneumonia (OR = 2.23 and 1.61, respectively) as well as hazard ratios (HR) on long-term follow-up for mortality and incidence of myocardial infarction (HR = 1.50 and 2.29, respectively). Kaplan-Meier estimation analysis also revealed similar results for both groups in terms of mid- and long-term survival (Breslow p = 0.062 and Log-Rank p = 0.064, respectively) and for incidence of myocardial infarction (Breslow p = 0.102 and Log-Rank p = 0.103, respectively). Our study suggests that use or not use of coronary artery bypass did not influence postoperative renal function. Odds of early outcomes were similar in both groups as well as incidence of myocardial infarction and mortality in long-term follow-up.
format Online
Article
Text
id pubmed-6786630
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-67866302019-10-19 Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study Merkle, Julia Sunny, Jaison Ehlscheid, Laura Sabashnikov, Anton Weber, Carolyn Eghbalzadeh, Kaveh Djordjevic, Ilija Liakopoulos, Oliver Choi, Yeong-Hoon Wahlers, Thorsten Zeriouh, Mohamed PLoS One Research Article The aim of our study was to compare early and long-term outcome of patients undergoing either on-pump or off-pump coronary artery bypass grafting with special focus on impairment of renal function. Five hundred ninety-three consecutive patients undergoing coronary artery bypass grafting were retrospectively analyzed. They were assigned either to on-pump (n = 281) or to off-pump (n = 312) group. Early and long-term outcomes were analyzed with special focus on renal function. Basic demographics and preoperative characteristics did not differ between groups (p>0.05) as well as postoperative renal parameters (p>0.05). Postoperative odds ratios (OR) of off-pump group in comparison to on-pump group were higher without reaching significance in terms of incidence of gastrointestinal complications and pneumonia (OR = 2.23 and 1.61, respectively) as well as hazard ratios (HR) on long-term follow-up for mortality and incidence of myocardial infarction (HR = 1.50 and 2.29, respectively). Kaplan-Meier estimation analysis also revealed similar results for both groups in terms of mid- and long-term survival (Breslow p = 0.062 and Log-Rank p = 0.064, respectively) and for incidence of myocardial infarction (Breslow p = 0.102 and Log-Rank p = 0.103, respectively). Our study suggests that use or not use of coronary artery bypass did not influence postoperative renal function. Odds of early outcomes were similar in both groups as well as incidence of myocardial infarction and mortality in long-term follow-up. Public Library of Science 2019-10-10 /pmc/articles/PMC6786630/ /pubmed/31600308 http://dx.doi.org/10.1371/journal.pone.0223806 Text en © 2019 Merkle et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Merkle, Julia
Sunny, Jaison
Ehlscheid, Laura
Sabashnikov, Anton
Weber, Carolyn
Eghbalzadeh, Kaveh
Djordjevic, Ilija
Liakopoulos, Oliver
Choi, Yeong-Hoon
Wahlers, Thorsten
Zeriouh, Mohamed
Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
title Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
title_full Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
title_fullStr Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
title_full_unstemmed Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
title_short Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
title_sort early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - a retrospective study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786630/
https://www.ncbi.nlm.nih.gov/pubmed/31600308
http://dx.doi.org/10.1371/journal.pone.0223806
work_keys_str_mv AT merklejulia earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT sunnyjaison earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT ehlscheidlaura earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT sabashnikovanton earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT webercarolyn earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT eghbalzadehkaveh earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT djordjevicilija earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT liakopoulosoliver earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT choiyeonghoon earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT wahlersthorsten earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy
AT zeriouhmohamed earlyandlongtermoutcomesofcoronaryarterybypasssurgerywithandwithoutuseofheartlungmachineandwithspecialrespecttorenalfunctionaretrospectivestudy