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Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection

Acute cerebral infarctions are rare in children, however they can occur as a complication of a Mycoplasma pneumoniae (MP) infection due to direct invasion, vasculitis, or a hypercoagulable state. We report on the case of a 5-year-old boy who had an extensive stroke in multiple cerebrovascular territ...

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Autores principales: Choi, Yu Hyeon, Jeong, Hyung Joo, Lee, Bongjin, An, Hong Yul, Lee, Eui Jun, Park, June Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Critical Care Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786714/
https://www.ncbi.nlm.nih.gov/pubmed/31723636
http://dx.doi.org/10.4266/kjccm.2016.00283
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author Choi, Yu Hyeon
Jeong, Hyung Joo
Lee, Bongjin
An, Hong Yul
Lee, Eui Jun
Park, June Dong
author_facet Choi, Yu Hyeon
Jeong, Hyung Joo
Lee, Bongjin
An, Hong Yul
Lee, Eui Jun
Park, June Dong
author_sort Choi, Yu Hyeon
collection PubMed
description Acute cerebral infarctions are rare in children, however they can occur as a complication of a Mycoplasma pneumoniae (MP) infection due to direct invasion, vasculitis, or a hypercoagulable state. We report on the case of a 5-year-old boy who had an extensive stroke in multiple cerebrovascular territories 10 days after the diagnosis of MP infection. Based on the suspicion that the cerebral infarction was associated with a macrolide-resistant MP infection, the patient was treated with levofloxacin, methyl-prednisolone, intravenous immunoglobulin, and enoxaparin. Despite this medical management, cerebral vascular narrowing progressed and a decompressive craniectomy became necessary for the patient’s survival. According to laboratory tests, brain magnetic resonance imaging, and clinical manifestations, the cerebral infarction in this case appeared to be due to the combined effects of hypercoagulability and cytokine-induced vascular inflammation.
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spelling pubmed-67867142019-11-13 Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection Choi, Yu Hyeon Jeong, Hyung Joo Lee, Bongjin An, Hong Yul Lee, Eui Jun Park, June Dong Korean J Crit Care Med Case Report Acute cerebral infarctions are rare in children, however they can occur as a complication of a Mycoplasma pneumoniae (MP) infection due to direct invasion, vasculitis, or a hypercoagulable state. We report on the case of a 5-year-old boy who had an extensive stroke in multiple cerebrovascular territories 10 days after the diagnosis of MP infection. Based on the suspicion that the cerebral infarction was associated with a macrolide-resistant MP infection, the patient was treated with levofloxacin, methyl-prednisolone, intravenous immunoglobulin, and enoxaparin. Despite this medical management, cerebral vascular narrowing progressed and a decompressive craniectomy became necessary for the patient’s survival. According to laboratory tests, brain magnetic resonance imaging, and clinical manifestations, the cerebral infarction in this case appeared to be due to the combined effects of hypercoagulability and cytokine-induced vascular inflammation. Korean Society of Critical Care Medicine 2017-05 2016-12-29 /pmc/articles/PMC6786714/ /pubmed/31723636 http://dx.doi.org/10.4266/kjccm.2016.00283 Text en Copyright © 2017 The Korean Society of Critical Care Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Choi, Yu Hyeon
Jeong, Hyung Joo
Lee, Bongjin
An, Hong Yul
Lee, Eui Jun
Park, June Dong
Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection
title Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection
title_full Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection
title_fullStr Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection
title_full_unstemmed Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection
title_short Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection
title_sort extensive and progressive cerebral infarction after mycoplasma pneumoniae infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786714/
https://www.ncbi.nlm.nih.gov/pubmed/31723636
http://dx.doi.org/10.4266/kjccm.2016.00283
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