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15-Deoxy-Δ(12,14)-prostaglandin J(2) Upregulates the Expression of 15-Hydroxyprostaglandin Dehydrogenase by Inducing AP-1 Activation and Heme Oxygenase-1 Expression in Human Colon Cancer Cells
BACKGROUND: Abnormal upregulation of prostaglandin E(2) (PGE(2)) is considered to be a key oncogenic event in the development and progression of inflammation-associated human colon cancer. It has been reported that 15-hydroxyprostaglandin dehydrogenase (15-PGDH), an enzyme catabolizing PGE(2), is ub...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society of Cancer Prevention
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786809/ https://www.ncbi.nlm.nih.gov/pubmed/31624724 http://dx.doi.org/10.15430/JCP.2019.24.3.183 |