BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma

Despite advances in therapy, glioblastoma remains an incurable disease with a dismal prognosis. Recent studies have implicated cancer stem cells within glioblastoma (glioma stem cells, GSCs) as mediators of therapeutic resistance and tumor progression. In this study, we investigated the role of the...

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Detalles Bibliográficos
Autores principales: Sachdeva, Rohit, Wu, Megan, Johnson, Kevin, Kim, Hyunsoo, Celebre, Angela, Shahzad, Uswa, Graham, Maya Srikanth, Kessler, John A., Chuang, Jeffrey H., Karamchandani, Jason, Bredel, Markus, Verhaak, Roel, Das, Sunit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787003/
https://www.ncbi.nlm.nih.gov/pubmed/31602000
http://dx.doi.org/10.1038/s41598-019-51270-1

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