Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens

In multiple tumor types, prediction of response to immune therapies relates to the presence, distribution and activation state of tumor infiltrating lymphocytes (TILs). Although such therapies are, to date, unsuccessful in gliomas, little is known on the immune contexture of TILs in these tumors. We...

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Detalles Bibliográficos
Autores principales: Weenink, Bas, Draaisma, Kaspar, Ooi, Han Z., Kros, Johan M., Sillevis Smitt, Peter A. E., Debets, Reno, French, Pim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787014/
https://www.ncbi.nlm.nih.gov/pubmed/31601888
http://dx.doi.org/10.1038/s41598-019-51063-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787014/
https://www.ncbi.nlm.nih.gov/pubmed/31601888
http://dx.doi.org/10.1038/s41598-019-51063-6

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