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Keratin 19 regulates cell cycle pathway and sensitivity of breast cancer cells to CDK inhibitors

Keratin 19 (K19) belongs to the keratin family of proteins, which maintains structural integrity of epithelia. In cancer, K19 is highly expressed in several types where it serves as a diagnostic marker. Despite the positive correlation between higher expression of K19 in tumor and worse patient surv...

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Detalles Bibliográficos
Autores principales: Sharma, Pooja, Alsharif, Sarah, Bursch, Karina, Parvathaneni, Swetha, Anastasakis, Dimitrios G., Chahine, Joeffrey, Fallatah, Arwa, Nicolas, Kevin, Sharma, Sudha, Hafner, Markus, Kallakury, Bhaskar, Chung, Byung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787034/
https://www.ncbi.nlm.nih.gov/pubmed/31601969
http://dx.doi.org/10.1038/s41598-019-51195-9