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Keratin 19 regulates cell cycle pathway and sensitivity of breast cancer cells to CDK inhibitors
Keratin 19 (K19) belongs to the keratin family of proteins, which maintains structural integrity of epithelia. In cancer, K19 is highly expressed in several types where it serves as a diagnostic marker. Despite the positive correlation between higher expression of K19 in tumor and worse patient surv...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787034/ https://www.ncbi.nlm.nih.gov/pubmed/31601969 http://dx.doi.org/10.1038/s41598-019-51195-9 |