Cargando…

DDIT3 (CHOP) contributes to retinal ganglion cell somal loss but not axonal degeneration in DBA/2J mice

Glaucoma is an age-related neurodegenerative disease characterized by the progressive loss of retinal ganglion cells (RGCs). Chronic ocular hypertension, an important risk factor for glaucoma, leads to RGC axonal injury at the optic nerve head. This insult triggers molecularly distinct cascades gove...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marola, Olivia J., Syc-Mazurek, Stephanie B., Libby, Richard T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787076/ https://www.ncbi.nlm.nih.gov/pubmed/31632741 http://dx.doi.org/10.1038/s41420-019-0220-4

Ejemplares similares

Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury
por: Syc-Mazurek, Stephanie B., et al.
Publicado: (2017)

Transcriptional control of retinal ganglion cell death after axonal injury
por: Syc-Mazurek, Stephanie B., et al.
Publicado: (2022)

Endothelin 1-induced retinal ganglion cell death is largely mediated by JUN activation
por: Marola, Olivia J., et al.
Publicado: (2020)

JUN is important for ocular hypertension-induced retinal ganglion cell degeneration
por: Syc-Mazurek, Stephanie B, et al.
Publicado: (2017)

Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice
por: Jakobs, Tatjana C., et al.
Publicado: (2005)

Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma
por: Howell, Gareth R., et al.
Publicado: (2007)

BclX(L) (Bcl2l1) gene therapy lessens retinal ganglion cell soma loss but not axonal degeneration after acute axonal injury
por: Marola, Olivia J., et al.
Publicado: (2022)

Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death
por: Syc-Mazurek, Stephanie B., et al.
Publicado: (2018)

Author Correction: Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death
por: Syc-Mazurek, Stephanie B., et al.
Publicado: (2019)

Microtubule Imaging Reveals Cytoskeletal Deficit Predisposing the Retinal Ganglion Cell Axons to Atrophy in DBA/2J
por: Sharoukhov, Denis, et al.
Publicado: (2018)

Retinal Ganglion Cell Dendritic Atrophy in DBA/2J Glaucoma
por: Williams, Pete A., et al.
Publicado: (2013)

Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric
por: Schlamp, Cassandra L, et al.
Publicado: (2006)

Diabetes Exacerbates the Intraocular Pressure-Independent Retinal Ganglion Cells Degeneration in the DBA/2J Model of Glaucoma
por: Amato, Rosario, et al.
Publicado: (2021)

Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma
por: Buchanan, Rebecca A., et al.
Publicado: (2019)

DDIT3/CHOP and the sarcoma fusion oncoprotein FUS-DDIT3/TLS-CHOP bind cyclin-dependent kinase 2
por: Bento, Christoffer, et al.
Publicado: (2009)

Vascular derived endothelin receptor A controls endothelin-induced retinal ganglion cell death
por: Marola, Olivia J., et al.
Publicado: (2022)

Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17
por: Niu, Jingwen, et al.
Publicado: (2020)

Early Involvement of Immune/Inflammatory Response Genes in Retinal Degeneration in DBA/2J Mice
por: Fan, W., et al.
Publicado: (2010)

Development and Degeneration of Retinal Ganglion Cell Axons in Xenopus tropicalis
por: Choi, Boyoon, et al.
Publicado: (2022)

Retinal ganglion cell axonal compression by retinal vessels in light-induced retinal degeneration
por: García-Ayuso, Diego, et al.
Publicado: (2011)

Microfluidic separation of axonal and somal compartments of neural progenitor cells differentiated in a 3D matrix
por: Lotlikar, Madhura S., et al.
Publicado: (2022)

BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps
por: Maes, Margaret E., et al.
Publicado: (2023)

Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons
por: Lambert, Wendi S, et al.
Publicado: (2011)

BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps
por: Maes, Margaret E., et al.
Publicado: (2023)

Retinal Ganglion Cells are Resistant to Photoreceptor Loss in Retinal Degeneration
por: Lin, Bin, et al.
Publicado: (2013)

Rescuing axons from degeneration does not affect retinal ganglion cell death
por: de Lima, S., et al.
Publicado: (2016)

Nicotinamide-Rich Diet in DBA/2J Mice Preserves Retinal Ganglion Cell Metabolic Function as Assessed by PERG Adaptation to Flicker
por: Chou, Tsung-Han, et al.
Publicado: (2020)

Distinct Cytoplasmic and Nuclear Functions of the Stress Induced Protein DDIT3/CHOP/GADD153
por: Jauhiainen, Alexandra, et al.
Publicado: (2012)

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model
por: Schaub, Julie A., et al.
Publicado: (2017)

Methamphetamine induces endoplasmic reticulum stress related gene CHOP/Gadd153/ddit3 in dopaminergic cells
por: Irie, Yasuyuki, et al.
Publicado: (2011)

Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice
por: Chi, Zai-Long, et al.
Publicado: (2010)

Loss of Retinogeniculate Synaptic Function in the DBA/2J Mouse Model of Glaucoma
por: Smith, Jennie C., et al.
Publicado: (2022)

Molecular mechanisms of retinal ganglion cell degeneration in glaucoma and future prospects for cell body and axonal protection
por: Munemasa, Yasunari, et al.
Publicado: (2013)

DBA/2J Mice Are Susceptible to Diabetic Nephropathy and Diabetic Exacerbation of IOP Elevation
por: Soto, Ileana, et al.
Publicado: (2014)

High dose expression of heme oxigenase-1 induces retinal degeneration through ER stress-related DDIT3
por: Li, Huirong, et al.
Publicado: (2021)

Effects of Dorzolamide on Retinal and Choroidal Blood Flow in the DBA/2J Mouse Model of Glaucoma
por: Chandra, Saurav, et al.
Publicado: (2016)

AAV2-Mediated Expression of HspB1 in RGCs Prevents Somal Damage and Axonal Transport Deficits in a Mouse Model of Ocular Hypertension
por: Nam, Mi-Hyun, et al.
Publicado: (2022)

Axonal transport of actin in rabbit retinal ganglion cells
Publicado: (1979)

Gene therapy and the regeneration of retinal ganglion cell axons
por: Harvey, Alan R.
Publicado: (2014)

Caspases in retinal ganglion cell death and axon regeneration
por: Thomas, Chloe N, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_h1he3v9pnbgotba5pd10ar8db1