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Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures
In peripherally acquired prion diseases, prions move through several tissues of the infected host, notably in the lymphoid tissue, long before the occurrence of neuroinvasion. Accumulation can even be restricted to the lymphoid tissue without neuroinvasion and clinical disease. Several experimental...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787085/ https://www.ncbi.nlm.nih.gov/pubmed/31601984 http://dx.doi.org/10.1038/s41598-019-51084-1 |