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Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen

Dendritic cells (DCs) are important initiators of adaptive immunity, and they possess a multitude of Pattern Recognition Receptors (PRR) to generate an adequate T cell mediated immunity against invading pathogens. PRR ligands are frequently conjugated to tumor-associated antigens in a vaccination st...

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Detalles Bibliográficos
Autores principales:	Li, Rui-Jun Eveline, Hogervorst, Tim P., Achilli, Silvia, Bruijns, Sven C., Arnoldus, Tim, Vivès, Corinne, Wong, Chung C., Thépaut, Michel, Meeuwenoord, Nico J., van den Elst, Hans, Overkleeft, Herman S., van der Marel, Gijs A., Filippov, Dmitri V., van Vliet, Sandra J., Fieschi, Franck, Codée, Jeroen D. C., van Kooyk, Yvette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787163/ https://www.ncbi.nlm.nih.gov/pubmed/31637232 http://dx.doi.org/10.3389/fchem.2019.00650

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