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mTOR/HDAC1 Crosstalk Mediated Suppression of ADH1A and ALDH2 Links Alcohol Metabolism to Hepatocellular Carcinoma Onset and Progression in silico

Hepatocellular carcinoma (HCC) is ranked the third deadliest cancer worldwide whose molecular pathogenesis is not fully understood. Although deregulated metabolic pathways have been implicated in HCC onset and progression, the mechanisms triggering this metabolic imbalance are yet to be explored. He...

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Detalles Bibliográficos
Autores principales:	Zahid, Kashif Rafiq, Yao, Shun, Khan, Abdur Rehman Raza, Raza, Umar, Gou, Deming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787164/ https://www.ncbi.nlm.nih.gov/pubmed/31637215 http://dx.doi.org/10.3389/fonc.2019.01000

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